產(chǎn)品編號(hào) | bs-0848R-BF350 |
英文名稱1 | Rabbit Anti-CSP/BF350 Conjugated antibody |
中文名稱 | BF350標(biāo)記的環(huán)子孢子蛋白(約氏瘧原蟲(chóng))抗體 |
別 名 | circumsporozoite protein (Plasmodium yoelii); Circumsporozoite protein; CS; CSP_PLAYO. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 昆蟲(chóng) |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Polyclonal |
交叉反應(yīng) | |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 37kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from the middle of Plasmodium yoelii CSP |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: No data available. Function: The circumsporozoite protein is the immunodominant surface antigen on the sporozoite (the infective stage of the malaria parasite that is transmitted from the mosquito to the vertebrate host). Similarity: Belongs to the plasmodium circumsporozoite protein family. Contains 1 TSP type-1 domain. Database links: UniProtKB/Swiss-Prot: P06914.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 瘧原蟲(chóng)的保護(hù)性抗原主要在蟲(chóng)體表面,統(tǒng)稱表面抗原。在瘧原蟲(chóng)生活史的發(fā)育各期,既有共同抗原,又有期特異性抗原,近年來(lái)經(jīng)研究發(fā)現(xiàn)了惡性瘧原蟲(chóng)和間日瘧原蟲(chóng)的配子表面的保護(hù)性抗原,已證明成熟子孢子體外附著的環(huán)子孢子蛋白(Circumsporozoite protein,CSP)具有明顯的抗原性。 紅內(nèi)期瘧原蟲(chóng)的不同發(fā)育階段,其抗原的質(zhì)和量均有變化,并可在被寄生的紅細(xì)胞膜上表露出來(lái)。裂殖子和子孢子均屬游離的瘧原蟲(chóng),因此誘導(dǎo)的宿主免疫均較明顯。已知有許多瘧原蟲(chóng)抗體可作用于裂殖子,使裂殖子凝集,阻止裂殖體釋放裂殖子。裂殖子表面抗原與其侵入紅細(xì)胞有關(guān)。 |