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Rabbit Anti-S100P binding protein/Cy3 Conjugated antibody (bs-6577R-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6577R-Cy3
英文名稱1 Rabbit Anti-S100P binding protein/Cy3 Conjugated antibody
中文名稱 Cy3標記的S100P結合蛋白抗體
別    名 S100P-binding protein; S100P-binding protein Riken;y S100PBP; S100PBPR; S1PBP_HUMAN.  
Journal
PMID
IF
Application
[IF=2.52] Mo, Jing, et al. "The in-vitro spheroid culture induces a more highly differentiated but tumorigenic population from melanoma cell lines." Melanoma Research (2013).  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  信號轉導  轉錄調節因子  結合蛋白  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human S100PBP/S100P binding protein (365-408aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
S100PBP was originally cloned from a pancreatic epithelioid carcinoma library and encodes a predicted 408 amino acid protein. RT-PCR detected S100PBP expression in brain, breast, spleen, and lung, but not in pancreas and liver. GFP-tagged S100PBP localized to nuclei of transfected HeLa cells.

Subunit:
Interacts with S100P.

Subcellular Location:
Nucleus. Note=Colocalizes with S100P in the nucleus.

Tissue Specificity:
Expressed in brain, spleen, and lung. Not detected in pancreas or liver. In pancreas, expressed predominantly in islet cells and to a lesser extent in acinar cells, but not expressed in ductal cells. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Detected in pancreatic ductal adenocarcinoma cells (at protein level). Not detected in non-neoplastic ductal epithelium (at protein level).

Database links:

UniProtKB/Swiss-Prot: Q96BU1.1

Entrez Gene: 64766 Human

Omim: 611889 Human

SwissProt: Q96BU1 Human

Unigee: 440880 Human

 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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