| 產品編號 | bs-2632R |
| 英文名稱 | Rabbit Anti-IL32 antibody |
| 中文名稱 | 白介素32抗體 |
| 別 名 | Interleukin-32/Natural killer cells protein 4; IL32; IL-32; IL 32; IL-32alpha; IL-32beta; IL-32delta; IL-32gamma; natural killer transcript 4; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; tumor necrosis factor alpha-inducing factor alpha; IL32_HUMAN. |
| 研究領域 | 心血管 免疫學 激酶和磷酸酶 細胞表面分子 自然殺傷細胞 t-淋巴細胞 上皮細胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human) |
| 產品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23kDa |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-32: 151-234/234 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
Interleukin 32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2. It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32. IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. As treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-alpha, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFN-gamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis. Function: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. Subcellular Location: Secreted. Tissue Specificity: Selectively expressed in lymphocytes. Expression is more prominent in immune cells than in non-immune cells. SWISS: P24001 Gene ID: 9235 Database links: Entrez Gene: 9235 Human Omim: 606001 Human SwissProt: P24001 Human Unigene: 943 Human IL-32是近年來發現的一種炎性細胞因子，主要由T淋巴細胞、NK細胞、單核細胞和上皮細胞等產生。IL-32誘導細胞因子的產生，在自身免疫方面起重要作用。< |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
